The mean objective voice scores measured at the first visit, at re‐examination after one and two weeks, and at follow‐up after two to six months did not significantly differ between the groups. One study investigated erythromycin for acute laryngitis in 106 adults. The trial also measured symptoms reported by participants and found no significant differences. No significant differences were found between the groups. A recording of each patient reading a standardised text was made at the first visit, during re‐examination after one and two weeks, and at follow‐up after two to six months. In one study of acute laryngitis in adults, 100 participants were randomised to receive penicillin V (800 mg twice daily for five days) or an identical placebo. We included a new trial presented only as a conference abstract in this update. We downgraded the studies because of limitations in study design or execution (risk of bias), imprecision and inconsistency of results. The quality of the evidence was very low for all outcomes. We included three RCTs (351 participants) that had moderate to high risk of bias.
